Acne scarring is a cosmetic problem that can affect 95% of acne patients and has a significant negative effect on patient´s quality of life.
Between 80% and 90% of patients with acne scars have atrophic scars compared to a minority who show hypertrophic and keloid scars.
Collagen loss is one of the main mechanisms involved in the pathogenesis of atrophic post-acne scars. Therefore, induction of collagen production is a promising tool for the treatment of post-acne atrophic scars.
Microinjection of low-viscosity hyaluronic acid offers a valuable technique for the treatment of atrophic acne scars, as it appears to induce longer-term effects by stimulating collagenogenesis by native fibroblasts.
SCIENTIFIC EVIDENCE
* SY Chuah, CL Goh. The impact of post-acne scars on the quality of life among young adults in Singapore. J Cutan Aesthet Surg. 2015;8:153-8.
* GJ Goodman. Treatment of acne scarring. Int J Dermatol.2011;50:1179-94.
* WA Mahamoud, RA El Barbary, NF Ibrahim. Fractional carbon dioxide laser combined with intradermal injection of autologous platelet-rich plasma versus noncross-linked hyaluronic acid in the treatment of atrophic postacne scars: A split face study. J Cosmet Dermatol. 2020;19:1341-52.
* S Halachmi, DB Amitai, M Lapidoth. Treatment of acne scars with hyaluronic acid: an improved approach. J Drugs Dermatol. 2013;12:121-3.
